MolNFT v1 · #86514 · protein
Crystal structure of truncated human crmp-5
4B91 · Dihydropyrimidinase-related protein 5: “Crystal structure of truncated human crmp-5”. X-ray diffraction, 14 pockets (best druggability 0.71). MolNFT v1 #86514 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4B91
- Type
- protein
- Length
- 949 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Dihydropyrimidinase-related protein 5
- UniProt
- Q9BPU6
- Pockets
- 14 · best druggability 0.71
Structure
x-ray diffraction · 2 distinct chains · 36% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Dihydropyrimidinase-related protein 5 | protein | 474 | 36% helix, 22% strand | Q9BPU6 |
| B | Dihydropyrimidinase-related protein 5 | protein | 475 | 36% helix, 22% strand | Q9BPU6 |
Pockets
14 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 55 | 0.71 | 0.98 | 20 | empty |
| 2 | 55 | 0.71 | 0.98 | 19 | empty |
| 3 | 395 | 0.59 | 0.76 | 46 | empty |
| 4 | 200 | 0.59 | 0.81 | 35 | empty |
| 5 | 189 | 0.52 | 0.78 | 20 | empty |
Interfaces
1 interface between chains.
- A–B · 1175 Ų buried · 8 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9BPU6
- Elsewhere: RCSB PDB 4B91 · PDBe 4B91 · UniProt Q9BPU6
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