MolNFT v1 · #86491 · protein

Ancestral (gnca) beta-lactamase class a

4B88: “Ancestral (gnca) beta-lactamase class a”. X-ray diffraction, 1 pocket (best druggability 0.25). MolNFT v1 #86491 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4B88
Type: protein
Length: 260 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Beta-lactamase
EC: 3.5.2.6
Pockets: 1 · best druggability 0.25

Structure

x-ray diffraction · 1 distinct chain · 45% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Beta-lactamase (EC 3.5.2.6)	protein	260	45% helix, 18% strand	—

Ligands and binding sites

FMT · Formic acid · additive · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	52	0.25	0.73	14	FMT

Compared structures

4B88 · Ancestral (GNCA) Beta-lactamase class A · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 4B88 · PDBe 4B88

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