MolNFT v1 · #86356 · protein
CETZ2 from haloferax volcanii - gtpgs bound protofilament
4B45 · Cell division protein ftsz: “CETZ2 from haloferax volcanii - gtpgs bound protofilament”. X-ray diffraction, 1 ligand (GSP), 4 pockets (best druggability 0.56). MolNFT v1 #86356 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 4B45
- Type
- protein
- Length
- 347 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Cell division protein ftsz
- UniProt
- D4GTC1
- Ligands
- GSP
- Pockets
- 4 · best druggability 0.56
Structure
x-ray diffraction · 2 distinct chains · 47% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cell division protein ftsz | protein | 334 | 49% helix, 24% strand | D4GTC1 |
| B | Cell division protein ftsz | protein | 13 | 0% helix, 8% strand | D4GTC1 |
Ligands and binding sites
- GSP · 5'-guanosine-diphosphate-monothiophosphate · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 204 | 0.56 | 0.80 | 31 | GSP |
| 2 | 80 | 0.38 | 0.78 | 12 | empty |
| 3 | 85 | 0.33 | 0.74 | 18 | empty |
| 4 | 55 | 0.28 | 0.74 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 608 Ų buried · 12 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt D4GTC1
- Elsewhere: RCSB PDB 4B45 · PDBe 4B45 · UniProt D4GTC1
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