MolNFT v1 · #8635 · protein

The three-dimensional structure of capsule-specific CMP:2-keto-3-deoxy-manno-octonic acid synthetase from escherichia COLI

1H6J · 3-deoxy-manno-octulosonate cytidylyltransferase: “The three-dimensional structure of capsule-specific CMP:2-keto-3-deoxy-manno-octonic acid synthetase from…”. X-ray diffraction, 1 pocket (best druggability 0.37). MolNFT v1 #8635 on…

PDB: 1H6J
Type: protein
Length: 482 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 3-deoxy-manno-octulosonate cytidylyltransferase
EC: 2.7.7.38
UniProt: P42216
Pockets: 1 · best druggability 0.37

Structure

x-ray diffraction · 1 distinct chain · 0% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	3-deoxy-manno-octulosonate cytidylyltransferase (EC 2.7.7.38)	protein	241	0% helix, 0% strand	P42216

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	94	0.37	0.73	31	empty

Interfaces

1 interface between chains.

A–B · 296 Å² buried · 0 hydrogen bonds · protein-protein

Compared structures

1H6J · The three-dimensional structure of capsule-specific CMP:2-keto-3-deoxy-manno-octonic acid… · the same entry in another collection · chain A against A, TM-score 1.00
P42216 · AlphaFold monomer V2.0 prediction for 3-deoxy-manno-octulosonate cytidylyltransferase… · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P42216
Elsewhere: RCSB PDB 1H6J · PDBe 1H6J · UniProt P42216

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