MolNFT v1 · #85942 · protein

Structure of the inactive pesticin T201A mutant

4ARM: “Structure of the inactive pesticin T201A mutant”. X-ray diffraction, 5 pockets (best druggability 0.72). MolNFT v1 #85942 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4ARM
Type: protein
Length: 693 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Pesticin
UniProt: Q57159
Pockets: 5 · best druggability 0.72

Structure

x-ray diffraction · 2 distinct chains · 39% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Pesticin	protein	346	38% helix, 18% strand	Q57159
B	Pesticin	protein	347	39% helix, 18% strand	Q57159

Pockets

5 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	778	0.72	0.78	77	empty
2	326	0.57	0.76	35	empty
3	375	0.54	0.74	47	empty
4	318	0.54	0.75	37	empty
5	242	0.54	0.77	33	empty

Interfaces

1 interface between chains.

A–B · 669 Å² buried · 15 hydrogen bonds · protein-protein

Compared structures

4ARM · Structure of the inactive pesticin T201A mutant · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q57159
Elsewhere: RCSB PDB 4ARM · PDBe 4ARM · UniProt Q57159

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