MolNFT v1 · #8584 · protein
Maltose phosphorylase from lactobacillus brevis
1H54: “Maltose phosphorylase from lactobacillus brevis”. X-ray diffraction, 2 ligands (K, PO4), 19 pockets (best druggability 0.77). MolNFT v1 #8584 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1H54
- Type
- protein
- Length
- 1,506 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Maltose phosphorylase
- EC
- 2.4.1.8
- Ligands
- K, PO4
- Pockets
- 19 · best druggability 0.77
Structure
x-ray diffraction · 2 distinct chains · 33% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Maltose phosphorylase (EC 2.4.1.8) | protein | 752 | 32% helix, 25% strand | — |
| B | Maltose phosphorylase (EC 2.4.1.8) | protein | 754 | 34% helix, 26% strand | — |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
19 pockets found on a 1 Å grid, 9 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 613 | 0.77 | 0.83 | 73 | PO4 |
| 2 | 1065 | 0.77 | 0.79 | 76 | empty |
| 3 | 78 | 0.74 | 0.97 | 18 | empty |
| 4 | 147 | 0.70 | 0.90 | 27 | empty |
| 5 | 175 | 0.69 | 0.88 | 33 | empty |
Interfaces
1 interface between chains.
- A–B · 2179 Ų buried · 27 hydrogen bonds · protein-protein
Compared structures
- 1H54 · Maltose phosphorylase from Lactobacillus brevis · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 1H54 · PDBe 1H54
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