MolNFT v1 · #85780 · protein
A megaviridae orfan gene encodes a new nucleotidyl transferase
4AMQ · L544: “A megaviridae orfan gene encodes a new nucleotidyl transferase”. X-ray diffraction, 2 ligands (MN, MG), 4 pockets (best druggability 0.53). MolNFT v1 #85780 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4AMQ
- Type
- protein
- Length
- 341 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- L544
- UniProt
- Q5UQA5
- Ligands
- MN, MG
- Pockets
- 4 · best druggability 0.53
Structure
x-ray diffraction · 1 distinct chain · 55% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | L544 | protein | 341 | 55% helix, 14% strand | Q5UQA5 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 357 | 0.53 | 0.73 | 37 | MN |
| 2 | 70 | 0.51 | 0.85 | 18 | empty |
| 3 | 98 | 0.37 | 0.75 | 17 | empty |
| 4 | 57 | 0.27 | 0.73 | 11 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Compared structures
- 4AMQ · A Megaviridae Orfan gene encodes a new nucleotidyl transferase · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5UQA5
- Elsewhere: RCSB PDB 4AMQ · PDBe 4AMQ · UniProt Q5UQA5
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