MolNFT v1 · #85445 · protein

Structure of the budding yeast NDC10 N-terminal domain

4ACO · Centromere DNA-binding protein complex CBF3 subunit a: “Structure of the budding yeast NDC10 N-terminal domain”. X-ray diffraction, 7 pockets (best druggability 0.61). MolNFT v1 #85445 on GenesisL1: 3D structure, binding sites and…

PDB: 4ACO
Type: protein
Length: 452 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Centromere DNA-binding protein complex CBF3 subunit a
UniProt: P32504
Pockets: 7 · best druggability 0.61

Structure

x-ray diffraction · 1 distinct chain · 55% helix, 6% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Centromere DNA-binding protein complex CBF3 subunit a	protein	452	55% helix, 6% strand	P32504

Pockets

7 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	284	0.61	0.79	27	empty
2	137	0.43	0.75	20	empty
3	131	0.41	0.75	22	empty
4	108	0.40	0.76	18	empty
5	72	0.34	0.76	16	empty

Compared structures

4ACO · Structure of the budding yeast Ndc10 N-terminal domain · the same entry in another collection · chain A against A, TM-score 1.00
P32504 · AlphaFold monomer V2.0 prediction for centromere DNA-binding protein complex CBF3 subunit… · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P32504
Elsewhere: RCSB PDB 4ACO · PDBe 4ACO · UniProt P32504

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