MolNFT v1 · #85414 · protein
Crystal structure of full length mouse strap (TTC5)
4ABN · Tetratricopeptide repeat protein 5: “Crystal structure of full length mouse strap (TTC5)”. X-ray diffraction, 7 pockets (best druggability 0.72). MolNFT v1 #85414 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4ABN
- Type
- protein
- Length
- 848 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tetratricopeptide repeat protein 5
- UniProt
- Q99LG4
- Pockets
- 7 · best druggability 0.72
Structure
x-ray diffraction · 2 distinct chains · 59% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tetratricopeptide repeat protein 5 | protein | 422 | 58% helix, 14% strand | Q99LG4 |
| B | Tetratricopeptide repeat protein 5 | protein | 426 | 59% helix, 13% strand | Q99LG4 |
Ligands and binding sites
- EDO · 1,2-ethanediol · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
7 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 736 | 0.72 | 0.78 | 53 | empty |
| 2 | 759 | 0.72 | 0.78 | 57 | empty |
| 3 | 401 | 0.61 | 0.76 | 32 | empty |
| 4 | 228 | 0.56 | 0.78 | 30 | empty |
| 5 | 169 | 0.51 | 0.78 | 27 | empty |
Interfaces
1 interface between chains.
- A–B · 422 Ų buried · 4 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q99LG4
- Elsewhere: RCSB PDB 4ABN · PDBe 4ABN · UniProt Q99LG4
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.