MolNFT v1 · #85236 · protein
Mutations in the neighbourhood of cota-laccase trinuclear site: D116E mutant
4A67 · Spore coat protein a: “Mutations in the neighbourhood of cota-laccase trinuclear site: D116E mutant”. X-ray diffraction, 2 ligands (CU, PER), 8 pockets (best druggability 0.54). MolNFT v1 #85236 on GenesisL1: 3D structure, binding…
- PDB
- 4A67
- Type
- protein
- Length
- 505 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Spore coat protein a
- EC
- 1.10.3.2
- UniProt
- P07788
- Ligands
- CU, PER
- Pockets
- 8 · best druggability 0.54
Structure
x-ray diffraction · 1 distinct chain · 9% helix, 41% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Spore coat protein a (EC 1.10.3.2) | protein | 505 | 9% helix, 41% strand | P07788 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
8 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 153 | 0.54 | 0.80 | 35 | empty |
| 2 | 181 | 0.54 | 0.79 | 33 | empty |
| 3 | 75 | 0.42 | 0.80 | 14 | empty |
| 4 | 126 | 0.41 | 0.75 | 28 | empty |
| 5 | 82 | 0.37 | 0.77 | 21 | empty |
Modifications
Observed in the structure: 1 disulfide, 1 modified (disulfide, oxidation).
Compared structures
- 4A67 · Mutations in the neighbourhood of CotA-laccase trinuclear site: D116E mutant · the same entry in another collection · chain A against A, TM-score 1.00
- P07788 · AlphaFold monomer V2.0 prediction for spore coat protein a (P07788) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P07788
- Elsewhere: RCSB PDB 4A67 · PDBe 4A67 · UniProt P07788
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