MolNFT v1 · #85087 · protein

NMR structure of protoporphyrin-IX bound murine P22HBP

4A1M · Heme-binding protein 1: “NMR structure of protoporphyrin-IX bound murine P22HBP”. Solution nmr, 2 pockets (best druggability 0.71). MolNFT v1 #85087 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4A1M
Type: protein
Length: 184 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Heme-binding protein 1
UniProt: Q9R257
Pockets: 2 · best druggability 0.71

Structure

solution nmr · 1 distinct chain · 19% helix, 28% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Heme-binding protein 1	protein	184	19% helix, 28% strand	Q9R257

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	232	0.71	0.87	31	empty
2	317	0.61	0.78	33	empty

Compared structures

4A1M · NMR Structure of protoporphyrin-IX bound murine p22HBP · the same entry in another collection · chain A against A, TM-score 1.00
Q9R257 · AlphaFold monomer V2.0 prediction for heme-binding protein 1 (Q9R257) · a predicted model of the same protein · chain A against A, TM-score 0.75

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9R257
Elsewhere: RCSB PDB 4A1M · PDBe 4A1M · UniProt Q9R257

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