MolNFT v1 · #85067 · protein
Structure of the carboxy-terminal domain of bacteriophage T7 fibre GP17 containing residues 371-553.
4A0T · Tail fiber protein: “Structure of the carboxy-terminal domain of bacteriophage T7 fibre GP17 containing residues 371-553.”. X-ray diffraction, 1 ligand (TMO), 3 pockets (best druggability 0.78). MolNFT v1 #85067 on GenesisL1: 3D…
- PDB
- 4A0T
- Type
- protein
- Length
- 548 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tail fiber protein
- UniProt
- P03748
- Ligands
- TMO
- Pockets
- 3 · best druggability 0.78
Structure
x-ray diffraction · 2 distinct chains · 8% helix, 49% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tail fiber protein | protein | 184 | 8% helix, 48% strand | P03748 |
| B, C | Tail fiber protein | protein | 182 | 8% helix, 49% strand | P03748 |
Ligands and binding sites
- TMO · trimethylamine oxide · ligand · 3 copies · chains A, B, C
- TRS · 2-amino-2-hydroxymethyl-propane-1,3-diol · additive · chains A, B, C
- 1PE · Pentaethylene glycol · additive · chains C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 150 | 0.78 | 0.95 | 34 | TRS |
| 2 | 61 | 0.73 | 0.98 | 23 | empty |
| 3 | 62 | 0.26 | 0.72 | 18 | empty |
Interfaces
3 interfaces between chains.
- A–B · 2650 Ų buried · 44 hydrogen bonds · protein-protein
- B–C · 2585 Ų buried · 43 hydrogen bonds · protein-protein
- A–C · 2557 Ų buried · 45 hydrogen bonds · protein-protein
Compared structures
- 4A0T · Structure of the carboxy-terminal domain of bacteriophage T7 fibre gp17 containing… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03748
- Elsewhere: RCSB PDB 4A0T · PDBe 4A0T · UniProt P03748
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.