MolNFT v1 · #85022 · RNA

Structure of an octamer RNA with tandem GG/UU mispairs

472D · RNA (5'-R(*GP*UP*GP*UP*UP*UP*AP*C)-3'): “Structure of an octamer RNA with tandem GG/UU mispairs”. X-ray diffraction, 1 pocket (best druggability 0.25). MolNFT v1 #85022 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 472D
Type: RNA
Length: 16 nucleotides
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: RNA (5'-R(*GP*UP*GP*UP*UP*UP*AP*C)-3'); RNA (5'-R(*GP*UP*AP*GP*GP*CP*AP*C)-3')
Pockets: 1 · best druggability 0.25

Structure

x-ray diffraction · 2 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	RNA (5'-R(GPUPGPUPUPUPAPC)-3')	rna	8	—	—
B	RNA (5'-R(GPUPAPGPGPCPAPC)-3')	rna	8	—	—

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	61	0.25	0.72	11	empty

Interfaces

1 interface between chains.

A–B · 385 Å² buried · 41 hydrogen bonds · nucleic-nucleic

Compared structures

472D · Structure of an octamer RNA with tandem GG/UU mispairs · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 472D · PDBe 472D

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