MolNFT v1 · #84901 · protein
Crystal structure of the N-terminal leucine rich repeats and immunoglobulin domain of netrin-G ligand-3
3ZYO · Leucine-rich repeat-containing protein 4B: “Crystal structure of the N-terminal leucine rich repeats and immunoglobulin domain of netrin-G ligand-3”. X-ray diffraction, 2 ligands (NAG, ZN), 2 pockets (best druggability 0.35). MolNFT…
- PDB
- 3ZYO
- Type
- protein
- Length
- 391 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Leucine-rich repeat-containing protein 4B
- UniProt
- P0C192
- Ligands
- NAG, ZN
- Pockets
- 2 · best druggability 0.35
Structure
x-ray diffraction · 1 distinct chain · 7% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Leucine-rich repeat-containing protein 4B | protein | 391 | 7% helix, 24% strand | P0C192 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 83 | 0.35 | 0.75 | 17 | empty |
| 2 | 51 | 0.24 | 0.73 | 16 | empty |
Modifications
Observed in the structure: 5 disulfide, 1 glycan (disulfide, N-glycosylation).
Compared structures
- 3ZYO · Crystal structure of the N-terminal leucine rich repeats and immunoglobulin domain of… · the same entry in another collection · chain A against A, TM-score 1.00
- P0C192 · AlphaFold monomer V2.0 prediction for leucine-rich repeat-containing protein 4B (P0C192) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0C192
- Elsewhere: RCSB PDB 3ZYO · PDBe 3ZYO · UniProt P0C192
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