MolNFT v1 · #84740 · protein
Aurora kinase selective inhibitors identified using a taxol- induced checkpoint sensitivity screen.
3ZTX: “Aurora kinase selective inhibitors identified using a taxol- induced checkpoint sensitivity screen.”. X-ray diffraction. MolNFT v1 #84740 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3ZTX
- Type
- protein
- Length
- 626 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- Q6DE08, O13024
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 270 | — | Q6DE08 |
| B | — | protein | 273 | — | Q6DE08 |
| C | — | protein | 40 | — | O13024 |
| D | — | protein | 43 | — | O13024 |
Compared structures
- 3ZTX · Aurora kinase selective inhibitors identified using a Taxol-induced checkpoint… · the same entry in another collection · chain D against D, TM-score 1.00
- Q6DE08 · AlphaFold monomer V2.0 prediction for aurora kinase B-a (Q6DE08) · a predicted model of the same protein · chain A against A, TM-score 0.99
- O13024 · AlphaFold monomer V2.0 prediction for inner centromere protein a (O13024) · a predicted model of the same protein · chain C against A, TM-score 0.58
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6DE08
- Every structure of UniProt O13024
- Elsewhere: RCSB PDB 3ZTX · PDBe 3ZTX · UniProt Q6DE08 · UniProt O13024
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