GL1X · GenesisL1 explorer

MolNFT v1 · #84328 · protein

Gamma 2 adaptin ear domain crystal structure with PRES1 SITE1 peptide npdwdfn

3ZHF · Ap-1 complex subunit gamma-like 2: “Gamma 2 adaptin ear domain crystal structure with PRES1 SITE1 peptide npdwdfn”. X-ray diffraction, 1 ligand (NH2). MolNFT v1 #84328 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
3ZHF
Type
protein
Length
129 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Ap-1 complex subunit gamma-like 2; Large envelope protein
UniProt
O75843, Q67953
Ligands
NH2

Structure

x-ray diffraction · 2 distinct chains · 2% helix, 48% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AAp-1 complex subunit gamma-like 2protein1232% helix, 50% strandO75843
BLarge envelope proteinprotein60% helix, 0% strandQ67953

Ligands and binding sites

  • NH2 · Amino group · ion · chains B
  • PEG · Di(hydroxyethyl)ether · additive · chains A
  • EDO · 1,2-ethanediol · additive · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

  • A–B · 464 Ų buried · 5 hydrogen bonds · protein-protein

Compared structures

  • 3ZHF · gamma 2 adaptin EAR domain crystal structure with preS1 site1 peptide NPDWDFN · the same entry in another collection · chain A against A, TM-score 1.00
  • O75843 · AlphaFold monomer V2.0 prediction for ap-1 complex subunit gamma-like 2 (O75843) · a predicted model of the same protein · chain A against A, TM-score 0.97

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