MolNFT v1 · #84309 · protein
Crystal structure of human interferon-induced protein IFIT5
3ZGQ · Interferon-induced protein with tetratricopeptide repeats 5: “Crystal structure of human interferon-induced protein IFIT5”. X-ray diffraction, 3 pockets (best druggability 0.72). MolNFT v1 #84309 on GenesisL1: 3D structure, binding…
- PDB
- 3ZGQ
- Type
- protein
- Length
- 475 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Interferon-induced protein with tetratricopeptide repeats 5
- UniProt
- Q13325
- Pockets
- 3 · best druggability 0.72
Structure
x-ray diffraction · 1 distinct chain · 76% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Interferon-induced protein with tetratricopeptide repeats 5 | protein | 475 | 76% helix, 0% strand | Q13325 |
Ligands and binding sites
- PEG · Di(hydroxyethyl)ether · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 421 | 0.72 | 0.82 | 42 | empty |
| 2 | 602 | 0.70 | 0.79 | 43 | empty |
| 3 | 78 | 0.31 | 0.73 | 24 | empty |
Compared structures
- 3ZGQ · Crystal structure of human interferon-induced protein IFIT5 · the same entry in another collection · chain A against A, TM-score 1.00
- Q13325 · AlphaFold monomer V2.0 prediction for interferon-induced protein with tetratricopeptide… · a predicted model of the same protein · chain A against A, TM-score 0.85
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q13325
- Elsewhere: RCSB PDB 3ZGQ · PDBe 3ZGQ · UniProt Q13325
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.