MolNFT v1 · #84245 · protein
Crystal structure of JAK3 kinase domain in complex with a pyrrolopyrazine-2-phenyl ether inhibitor
3ZEP: “Crystal structure of JAK3 kinase domain in complex with a pyrrolopyrazine-2-phenyl ether inhibitor”. X-ray diffraction. MolNFT v1 #84245 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3ZEP
- Type
- protein
- Length
- 1,098 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- UniProt
- P52333
Structure
x-ray diffraction · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 276 | — | P52333 |
| B | — | protein | 270 | — | P52333 |
| C | — | protein | 278 | — | P52333 |
| D | — | protein | 274 | — | P52333 |
Compared structures
- 3ZEP · Crystal Structure of JAK3 Kinase Domain in Complex with a Pyrrolopyrazine-2-phenyl Ether… · the same entry in another collection · chain D against D, TM-score 1.00
- P52333 · AlphaFold monomer V2.0 prediction for tyrosine-protein kinase JAK3 (P52333) · a predicted model of the same protein · chain D against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P52333
- Elsewhere: RCSB PDB 3ZEP · PDBe 3ZEP · UniProt P52333
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