MolNFT v1 · #84147 · protein

A new family of proteins related to the heat-like repeat DNA glycosylases with affinity for branched DNA structures

3ZBO · Alkf: “A new family of proteins related to the heat-like repeat DNA glycosylases with affinity for branched DNA…”. X-ray diffraction, 1 ligand (CL), 6 pockets (best druggability 0.84). MolNFT v1 #84147 on GenesisL1: 3D structure…

PDB: 3ZBO
Type: protein
Length: 471 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Alkf
UniProt: Q81BA8
Ligands: CL
Pockets: 6 · best druggability 0.84

Structure

x-ray diffraction · 2 distinct chains · 69% helix, 4% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Alkf	protein	236	69% helix, 3% strand	Q81BA8
B	Alkf	protein	235	68% helix, 6% strand	Q81BA8

Ligands and binding sites

CL · Chloride ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1161	0.84	0.85	86	empty
2	106	0.38	0.75	20	empty
3	95	0.36	0.75	18	empty
4	87	0.35	0.75	21	empty
5	59	0.29	0.74	17	empty

Interfaces

1 interface between chains.

A–B · 1197 Å² buried · 11 hydrogen bonds · protein-protein

Compared structures

3ZBO · A new family of proteins related to the HEAT-like repeat DNA glycosylases with affinity… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q81BA8
Elsewhere: RCSB PDB 3ZBO · PDBe 3ZBO · UniProt Q81BA8

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.