MolNFT v1 · #83903 · protein
Crystal structure of lysz from thermus thermophilus complex with lysw
3WWN · Putative acetylglutamate kinase-like protein: “Crystal structure of lysz from thermus thermophilus complex with lysw”. X-ray diffraction, 2 ligands (ZN, SO4), 2 pockets (best druggability 0.80). MolNFT v1 #83903 on GenesisL1: 3D…
- PDB
- 3WWN
- Type
- protein
- Length
- 317 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative acetylglutamate kinase-like protein; Orff
- UniProt
- O50147, Q9ZND7
- Ligands
- ZN, SO4
- Pockets
- 2 · best druggability 0.80
Structure
x-ray diffraction · 2 distinct chains · 30% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Putative acetylglutamate kinase-like protein | protein | 263 | 36% helix, 25% strand | O50147 |
| B | Orff | protein | 54 | 0% helix, 35% strand | Q9ZND7 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 787 | 0.80 | 0.83 | 88 | SO4 |
| 2 | 73 | 0.41 | 0.80 | 20 | empty |
Interfaces
1 interface between chains.
- A–B · 901 Ų buried · 12 hydrogen bonds · protein-protein
Compared structures
- 3WWN · Crystal structure of LysZ from Thermus thermophilus complex with LysW · the same entry in another collection · chain A against A, TM-score 1.00
- O50147 · AlphaFold monomer V2.0 prediction for [lysw]-aminoadipate kinase (O50147) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O50147
- Every structure of UniProt Q9ZND7
- Elsewhere: RCSB PDB 3WWN · PDBe 3WWN · UniProt O50147 · UniProt Q9ZND7
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.