MolNFT v1 · #83874 · protein

Crystal structure of RUCO/APO-R52CFR

3WVU · Ferritin light chain: “Crystal structure of RUCO/APO-R52CFR”. X-ray diffraction, 3 ligands (CD, RU, SO4), 3 pockets (best druggability 0.42). MolNFT v1 #83874 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3WVU
Type: protein
Length: 173 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ferritin light chain
UniProt: P02791
Ligands: CD, RU, SO4
Pockets: 3 · best druggability 0.42

Structure

x-ray diffraction · 1 distinct chain · 74% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ferritin light chain	protein	173	74% helix, 0% strand	P02791

Ligands and binding sites

CD · Cadmium ion · metal · 3 copies · chains A
RU · Ruthenium ion · metal · 2 copies · chains A
SO4 · Sulfate ion · ion · chains A
EDO · 1,2-ethanediol · additive · 8 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	92	0.42	0.78	13	EDO
2	50	0.29	0.75	15	empty
3	50	0.29	0.75	14	EDO

Compared structures

3WVU · Crystal Structure of RuCO/apo-R52CFr · the same entry in another collection · chain A against A, TM-score 1.00
P02791 · AlphaFold monomer V2.0 prediction for ferritin light chain (P02791) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P02791
Elsewhere: RCSB PDB 3WVU · PDBe 3WVU · UniProt P02791

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