MolNFT v1 · #83740 · protein

Minute virus of mice non-structural protein-1N-terminal nuclease domain reveals a unique ZN2+ coordination in the active site pocket and shows a novel mode of DNA recognition at the origin of replication

3WRS · Non-capsid protein ns-1: “Minute virus of mice non-structural protein-1N-terminal nuclease domain reveals a unique ZN2+ coordination in…”. X-ray diffraction, 1 ligand (CO), 1 pocket (best druggability 0.39). MolNFT v1 #83740 on…

PDB: 3WRS
Type: protein
Length: 248 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Non-capsid protein ns-1
UniProt: P03134
Ligands: CO
Pockets: 1 · best druggability 0.39

Structure

x-ray diffraction · 1 distinct chain · 45% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Non-capsid protein ns-1	protein	248	45% helix, 21% strand	P03134

Ligands and binding sites

CO · Cobalt (II) ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	65	0.39	0.79	14	empty

Compared structures

3WRS · Minute virus of mice non-structural protein-1N-terminal nuclease domain reveals a unique… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P03134
Elsewhere: RCSB PDB 3WRS · PDBe 3WRS · UniProt P03134

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