MolNFT v1 · #83426 · protein

P453H/I471T mutant of PB2 middle domain from influenza virus A/PUERTO RICO/8/34(H1N1)

3WI0 · Polymerase basic protein 2: “P453H/I471T mutant of PB2 middle domain from influenza virus A/PUERTO RICO/8/34(H1N1)”. X-ray diffraction, 1 pocket (best druggability 0.52). MolNFT v1 #83426 on GenesisL1: 3D structure, binding sites…

PDB: 3WI0
Type: protein
Length: 169 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Polymerase basic protein 2
UniProt: P03428
Pockets: 1 · best druggability 0.52

Structure

x-ray diffraction · 1 distinct chain · 24% helix, 41% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Polymerase basic protein 2	protein	169	24% helix, 41% strand	P03428

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	167	0.52	0.78	19	empty

Compared structures

3WI0 · P453H/I471T mutant of PB2 middle domain from influenza virus A/Puerto Rico/8/34(H1N1) · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P03428
Elsewhere: RCSB PDB 3WI0 · PDBe 3WI0 · UniProt P03428

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