MolNFT v1 · #83146 · protein

Structure of oryzias latipes enteropeptidase light chain

3W94 · Enteropeptidase-1: “Structure of oryzias latipes enteropeptidase light chain”. X-ray diffraction, 5 pockets (best druggability 0.78). MolNFT v1 #83146 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3W94
Type: protein
Length: 470 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Enteropeptidase-1
UniProt: A4UWM5
Pockets: 5 · best druggability 0.78

Structure

x-ray diffraction · 1 distinct chain · 11% helix, 36% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Enteropeptidase-1	protein	235	11% helix, 36% strand	A4UWM5

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	381	0.78	0.87	44	empty
2	111	0.42	0.77	29	empty
3	93	0.37	0.76	27	empty
4	67	0.30	0.73	15	empty
5	61	0.28	0.74	13	empty

Interfaces

1 interface between chains.

A–B · 667 Å² buried · 8 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 8 disulfide (disulfide).

Compared structures

3W94 · Structure of Oryzias latipes enteropeptidase light chain · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A4UWM5
Elsewhere: RCSB PDB 3W94 · PDBe 3W94 · UniProt A4UWM5

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