MolNFT v1 · #8310 · protein
M. smegmatis arylamine N-acetyl transferase
1GX3 · Arylamine N-acetyltransferase: “M. smegmatis arylamine N-acetyl transferase”. X-ray diffraction, 6 pockets (best druggability 0.65). MolNFT v1 #8310 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1GX3
- Type
- protein
- Length
- 1,098 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Arylamine N-acetyltransferase
- EC
- 2.3.1.5
- UniProt
- O86309
- Pockets
- 6 · best druggability 0.65
Structure
x-ray diffraction · 2 distinct chains · 32% helix, 27% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Arylamine N-acetyltransferase (EC 2.3.1.5) | protein | 276 | 32% helix, 27% strand | O86309 |
| B, C, D | Arylamine N-acetyltransferase (EC 2.3.1.5) | protein | 274 | 32% helix, 27% strand | O86309 |
Pockets
6 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 373 | 0.65 | 0.79 | 36 | empty |
| 2 | 355 | 0.64 | 0.79 | 37 | empty |
| 3 | 308 | 0.62 | 0.79 | 36 | empty |
| 4 | 293 | 0.62 | 0.79 | 35 | empty |
| 5 | 74 | 0.33 | 0.75 | 15 | empty |
Interfaces
2 interfaces between chains.
- A–B · 461 Ų buried · 9 hydrogen bonds · protein-protein
- C–D · 373 Ų buried · 8 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O86309
- Elsewhere: RCSB PDB 1GX3 · PDBe 1GX3 · UniProt O86309
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