MolNFT v1 · #82924 · protein
Crystal structure of T brucei ATG8.2 in complex with E COLI S10
3W1Y · Microtubule-associated protein 1A/1B, light chain 3: “Crystal structure of T brucei ATG8.2 in complex with E COLI S10”. X-ray diffraction, 3 pockets (best druggability 0.69). MolNFT v1 #82924 on GenesisL1: 3D structure, binding…
- PDB
- 3W1Y
- Type
- protein
- Length
- 314 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Microtubule-associated protein 1A/1B, light chain 3; 30S ribosomal protein S10
- UniProt
- Q57WE7, P0A7R5
- Pockets
- 3 · best druggability 0.69
Structure
x-ray diffraction · 3 distinct chains · 35% helix, 33% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Microtubule-associated protein 1A/1B, light chain 3 | protein | 120 | 38% helix, 26% strand | Q57WE7 |
| B | Microtubule-associated protein 1A/1B, light chain 3 | protein | 104 | 37% helix, 30% strand | Q57WE7 |
| C | 30S ribosomal protein S10 | protein | 90 | 28% helix, 48% strand | P0A7R5 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 649 | 0.69 | 0.77 | 56 | empty |
| 2 | 171 | 0.49 | 0.77 | 30 | empty |
| 3 | 115 | 0.37 | 0.74 | 26 | empty |
Interfaces
3 interfaces between chains.
- A–C · 552 Ų buried · 3 hydrogen bonds · protein-protein
- A–B · 427 Ų buried · 0 hydrogen bonds · protein-protein
- B–C · 119 Ų buried · 1 hydrogen bond · protein-protein
Compared structures
- 3W1Y · Crystal structure of T brucei ATG8.2 in complex with E coli S10 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q57WE7
- Every structure of UniProt P0A7R5
- Elsewhere: RCSB PDB 3W1Y · PDBe 3W1Y · UniProt Q57WE7 · UniProt P0A7R5
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