MolNFT v1 · #82772 · protein

Crystal structure of kluyveromyces marxianus ATG7NTD-ATG10 complex

3VX7 · E1: “Crystal structure of kluyveromyces marxianus ATG7NTD-ATG10 complex”. X-ray diffraction, 6 pockets (best druggability 0.72). MolNFT v1 #82772 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3VX7
Type: protein
Length: 419 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: E1; E2
Pockets: 6 · best druggability 0.72

Structure

x-ray diffraction · 2 distinct chains · 24% helix, 34% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	E1	protein	268	22% helix, 34% strand	—
B	E2	protein	151	27% helix, 34% strand	—

Pockets

6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	596	0.72	0.80	72	empty
2	151	0.49	0.78	26	empty
3	112	0.46	0.79	20	empty
4	110	0.44	0.78	23	empty
5	98	0.43	0.78	18	empty

Interfaces

1 interface between chains.

A–B · 903 Å² buried · 14 hydrogen bonds · protein-protein

Compared structures

3VX7 · Crystal structure of Kluyveromyces marxianus Atg7NTD-Atg10 complex · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 3VX7 · PDBe 3VX7

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