MolNFT v1 · #82742 · protein

Crystal structure of sugar epimerase from ruminal bacterium

3VW5 · Cellobiose 2-epimerase: “Crystal structure of sugar epimerase from ruminal bacterium”. X-ray diffraction, 10 pockets (best druggability 0.80). MolNFT v1 #82742 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3VW5
Type: protein
Length: 1,167 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cellobiose 2-epimerase
EC: 5.1.3.11
UniProt: A8CF79
Pockets: 10 · best druggability 0.80

Structure

x-ray diffraction · 1 distinct chain · 54% helix, 14% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C	Cellobiose 2-epimerase (EC 5.1.3.11)	protein	389	54% helix, 14% strand	A8CF79

Pockets

10 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	977	0.80	0.82	68	empty
2	348	0.66	0.80	30	empty
3	329	0.65	0.80	31	empty
4	304	0.65	0.81	30	empty
5	104	0.56	0.85	20	empty

Interfaces

3 interfaces between chains.

B–C · 843 Å² buried · 12 hydrogen bonds · protein-protein
A–B · 817 Å² buried · 12 hydrogen bonds · protein-protein
A–C · 803 Å² buried · 12 hydrogen bonds · protein-protein

Compared structures

3VW5 · Crystal structure of sugar epimerase from ruminal bacterium · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A8CF79
Elsewhere: RCSB PDB 3VW5 · PDBe 3VW5 · UniProt A8CF79

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.