MolNFT v1 · #82674 · protein
Short peptide HIV entry inhibitor mt-SC22EK with a M-T hook
3VU6 · Transmembrane protein GP41: “Short peptide HIV entry inhibitor mt-SC22EK with a M-T hook”. X-ray diffraction, 3 ligands (ACE, NH2, SO4). MolNFT v1 #82674 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3VU6
- Type
- protein
- Length
- 62 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Transmembrane protein GP41; MTSC22
- UniProt
- P03375
- Ligands
- ACE, NH2, SO4
Structure
x-ray diffraction · 2 distinct chains · 92% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transmembrane protein GP41 | protein | 38 | 95% helix, 0% strand | P03375 |
| B | MTSC22 | protein | 24 | 88% helix, 0% strand | — |
Ligands and binding sites
- ACE · Acetyl group · ligand · chains B
- NH2 · Amino group · ion · chains A
- SO4 · Sulfate ion · ion · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–B · 421 Ų buried · 2 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 covalent (covalent ligand).
Compared structures
- 3VU6 · Short peptide HIV entry inhibitor MT-SC22EK with a M-T hook · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03375
- Elsewhere: RCSB PDB 3VU6 · PDBe 3VU6 · UniProt P03375
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