MolNFT v1 · #82482 · protein + DNA

X-ray crystal structure of wild type hrtr in the apo form with the target DNA.

3VOK · Transcriptional regulator: “X-ray crystal structure of wild type hrtr in the apo form with the target DNA.”. X-ray diffraction, 1 pocket (best druggability 0.58). MolNFT v1 #82482 on GenesisL1: 3D structure, binding sites and…

PDB: 3VOK
Type: protein + DNA
Length: 191 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Transcriptional regulator; 5'-D(*AP*TP*GP*AP*CP*AP*CP*TP*GP*TP*GP*TP*CP*AP*T)-3'
UniProt: Q9CHR1
Pockets: 1 · best druggability 0.58

Structure

x-ray diffraction · 2 distinct chains · 74% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Transcriptional regulator	protein	176	74% helix, 0% strand	Q9CHR1
U	5'-D(APTPGPAPCPAPCPTPGPTPGPTPCPAP*T)-3'	dna	15	—	—

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	148	0.58	0.82	21	empty

Interfaces

1 interface between chains.

A–U · 185 Å² buried · 1 hydrogen bond · protein-nucleic

Compared structures

3VOK · X-ray Crystal Structure of Wild Type HrtR in the Apo Form with the Target DNA. · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9CHR1
Elsewhere: RCSB PDB 3VOK · PDBe 3VOK · UniProt Q9CHR1

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.