MolNFT v1 · #82436 · protein
Fungal antifreeze protein exerts hyperactivity by constructing an inequable beta-helix
3VN3: “Fungal antifreeze protein exerts hyperactivity by constructing an inequable beta-helix”. X-ray diffraction, 1 pocket (best druggability 0.54). MolNFT v1 #82436 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3VN3
- Type
- protein
- Length
- 446 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Antifreeze protein
- UniProt
- Q76CE6
- Pockets
- 1 · best druggability 0.54
Structure
x-ray diffraction · 1 distinct chain · 16% helix, 42% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Antifreeze protein | protein | 223 | 16% helix, 42% strand | Q76CE6 |
Ligands and binding sites
- EDO · 1,2-ethanediol · additive · 7 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 399 | 0.54 | 0.73 | 41 | EDO |
Interfaces
1 interface between chains.
- A–B · 54 Ų buried · 0 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 modified (nonstandard).
Compared structures
- 3VN3 · Fungal antifreeze protein exerts hyperactivity by constructing an inequable beta-helix · the same entry in another collection · chain A against A, TM-score 1.00
- Q76CE6 · AlphaFold monomer V2.0 prediction for ice-binding protein K3-B1 (Q76CE6) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q76CE6
- Elsewhere: RCSB PDB 3VN3 · PDBe 3VN3 · UniProt Q76CE6
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