MolNFT v1 · #82426 · protein
Crystal structure of staphylococcus aureus membrane-bound transglycosylase in complex with moenomycin
3VMR · Monofunctional glycosyltransferase: “Crystal structure of staphylococcus aureus membrane-bound transglycosylase in complex with moenomycin”. X-ray diffraction, 1 ligand (M0E), 3 pockets (best druggability 0.56). MolNFT v1 #82426 on…
- PDB
- 3VMR
- Type
- protein
- Length
- 227 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Monofunctional glycosyltransferase
- EC
- 2.4.-.-
- UniProt
- Q99T05
- Ligands
- M0E
- Pockets
- 3 · best druggability 0.56
Structure
x-ray diffraction · 1 distinct chain · 52% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Monofunctional glycosyltransferase (EC 2.4.-.-) | protein | 227 | 52% helix, 1% strand | Q99T05 |
Ligands and binding sites
- M0E · Moenomycin · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 323 | 0.56 | 0.76 | 41 | M0E |
| 2 | 153 | 0.56 | 0.81 | 28 | empty |
| 3 | 76 | 0.30 | 0.73 | 21 | empty |
Compared structures
- 3VMR · Crystal structure of Staphylococcus aureus membrane-bound transglycosylase in complex… · the same entry in another collection · chain A against A, TM-score 1.00
- Q99T05 · AlphaFold monomer V2.0 prediction for monofunctional glycosyltransferase (Q99T05) · a predicted model of the same protein · chain A against A, TM-score 0.94
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q99T05
- Elsewhere: RCSB PDB 3VMR · PDBe 3VMR · UniProt Q99T05
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.