MolNFT v1 · #8240 · protein

Crystal structure of C-myb R2R3

1GV2 · Myb proto-oncogene protein: “Crystal structure of C-myb R2R3”. X-ray diffraction, 1 ligand (NA), 2 pockets (best druggability 0.34). MolNFT v1 #8240 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1GV2
Type: protein
Length: 102 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Myb proto-oncogene protein
UniProt: P06876
Ligands: NA
Pockets: 2 · best druggability 0.34

Structure

x-ray diffraction · 1 distinct chain · 61% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Myb proto-oncogene protein	protein	102	61% helix, 0% strand	P06876

Ligands and binding sites

NA · Sodium ion · metal · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	86	0.34	0.74	15	empty
2	56	0.29	0.75	12	empty

Compared structures

1GV2 · Crystal structure of C-myb R2R3 · the same entry in another collection · chain A against A, TM-score 1.00
P06876 · AlphaFold monomer V2.0 prediction for transcriptional activator myb (P06876) · a predicted model of the same protein · chain A against A, TM-score 0.60

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P06876
Elsewhere: RCSB PDB 1GV2 · PDBe 1GV2 · UniProt P06876

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