MolNFT v1 · #82374 · protein

Crystal structure of the superfamily 1 helicase from tomato mosaic virus

3VKW · Replicase large subunit: “Crystal structure of the superfamily 1 helicase from tomato mosaic virus”. X-ray diffraction, 1 ligand (SO4), 5 pockets (best druggability 0.59). MolNFT v1 #82374 on GenesisL1: 3D structure, binding sites…

PDB: 3VKW
Type: protein
Length: 440 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Replicase large subunit
EC: 2.1.1.-, 2.7.7.-, 3.6.4.13
UniProt: P03587
Ligands: SO4
Pockets: 5 · best druggability 0.59

Structure

x-ray diffraction · 1 distinct chain · 31% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Replicase large subunit (EC 2.1.1.-, 2.7.7.-, 3.6.4.13)	protein	440	31% helix, 22% strand	P03587

Ligands and binding sites

SO4 · Sulfate ion · ion · 7 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	255	0.59	0.79	51	SO4
2	331	0.55	0.75	26	SO4
3	56	0.37	0.79	15	empty
4	62	0.37	0.79	21	empty
5	76	0.30	0.73	15	empty

Compared structures

3VKW · Crystal Structure of the Superfamily 1 Helicase from Tomato Mosaic Virus · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P03587
Elsewhere: RCSB PDB 3VKW · PDBe 3VKW · UniProt P03587

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.