MolNFT v1 · #82299 · protein

Crystal structure of the pH domain of evectin-2 from human

3VIA · Pleckstrin homology domain-containing family B member 2: “Crystal structure of the pH domain of evectin-2 from human”. X-ray diffraction, 1 pocket (best druggability 0.35). MolNFT v1 #82299 on GenesisL1: 3D structure, binding sites…

PDB: 3VIA
Type: protein
Length: 224 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Pleckstrin homology domain-containing family B member 2
UniProt: Q96CS7
Pockets: 1 · best druggability 0.35

Structure

x-ray diffraction · 1 distinct chain · 21% helix, 44% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Pleckstrin homology domain-containing family B member 2	protein	112	21% helix, 44% strand	Q96CS7

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	66	0.35	0.77	16	empty

Interfaces

1 interface between chains.

A–B · 764 Å² buried · 8 hydrogen bonds · protein-protein

Compared structures

3VIA · Crystal structure of the PH domain of Evectin-2 from human · the same entry in another collection · chain A against A, TM-score 1.00
Q96CS7 · AlphaFold monomer V2.0 prediction for pleckstrin homology domain- containing family B… · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q96CS7
Elsewhere: RCSB PDB 3VIA · PDBe 3VIA · UniProt Q96CS7

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