MolNFT v1 · #81942 · protein

Crystal structure of threonine synthase (thrc) from from burkholderia thailandensis

3V7N: “Crystal structure of threonine synthase (thrc) from from burkholderia thailandensis”. X-ray diffraction, 1 ligand (BO3), 4 pockets (best druggability 0.65). MolNFT v1 #81942 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 3V7N
Type: protein
Length: 464 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Threonine synthase
EC: 4.2.3.1
UniProt: Q2SWH9
Ligands: BO3
Pockets: 4 · best druggability 0.65

Structure

x-ray diffraction · 1 distinct chain · 45% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Threonine synthase (EC 4.2.3.1)	protein	464	45% helix, 16% strand	Q2SWH9

Ligands and binding sites

BO3 · Boric acid · ion · 2 copies · chains A
EDO · 1,2-ethanediol · additive · 5 copies · chains A
MLA · Malonic acid · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	547	0.65	0.76	64	MLA, BO3
2	53	0.51	0.87	18	empty
3	89	0.38	0.76	19	empty
4	83	0.31	0.73	22	empty

Compared structures

3V7N · Crystal structure of Threonine synthase (thrC) from from Burkholderia thailandensis · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q2SWH9
Elsewhere: RCSB PDB 3V7N · PDBe 3V7N · UniProt Q2SWH9

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