MolNFT v1 · #81716 · protein
Crystal structure of ciona intestinalis voltage sensor-containing phosphatase (ci-vsp), residues 241-576(C363S), form II
3V0F · Voltage-sensor containing phosphatase: “Crystal structure of ciona intestinalis voltage sensor-containing phosphatase (ci-vsp), residues…”. X-ray diffraction, 1 ligand (PO4), 8 pockets (best druggability 0.46). MolNFT v1 #81716 on…
- PDB
- 3V0F
- Type
- protein
- Length
- 654 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Voltage-sensor containing phosphatase
- UniProt
- Q4W8A1
- Ligands
- PO4
- Pockets
- 8 · best druggability 0.46
Structure
x-ray diffraction · 2 distinct chains · 26% helix, 31% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Voltage-sensor containing phosphatase | protein | 331 | 26% helix, 30% strand | Q4W8A1 |
| B | Voltage-sensor containing phosphatase | protein | 323 | 26% helix, 32% strand | Q4W8A1 |
Ligands and binding sites
- PO4 · Phosphate ion · ion · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
8 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 164 | 0.46 | 0.76 | 27 | empty |
| 2 | 161 | 0.46 | 0.76 | 24 | empty |
| 3 | 117 | 0.43 | 0.77 | 26 | empty |
| 4 | 78 | 0.39 | 0.78 | 26 | empty |
| 5 | 110 | 0.38 | 0.76 | 23 | PO4 |
Interfaces
1 interface between chains.
- A–B · 346 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
- 3V0F · Crystal structure of Ciona intestinalis voltage sensor-containing phosphatase (Ci-VSP)… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q4W8A1
- Elsewhere: RCSB PDB 3V0F · PDBe 3V0F · UniProt Q4W8A1
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