MolNFT v1 · #81665 · DNA
Crystal structure of an intramolecular human telomeric DNA G- quadruplex bound by the naphthalene diimide compound, MM41
3UYH · Human telomeric DNA sequence: “Crystal structure of an intramolecular human telomeric DNA G- quadruplex bound by the naphthalene diimide…”. X-ray diffraction, 2 ligands (0DX, K), 1 pocket (best druggability 0.26). MolNFT v1 #81665…
- PDB
- 3UYH
- Type
- DNA
- Length
- 21 nucleotides
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Human telomeric DNA sequence
- Ligands
- 0DX, K
- Pockets
- 1 · best druggability 0.26
Structure
x-ray diffraction · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Human telomeric DNA sequence | dna | 21 | — | — |
Ligands and binding sites
- 0DX · 4,9-bis{[3-(4-methylpiperazin-1-yl)propyl]amino}-2,7-bis[3-(morpholin-4-yl)propyl]benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetrone · ligand · chains A
- K · Potassium ion · metal · 3 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 52 | 0.26 | 0.74 | 7 | empty |
Compared structures
- 3UYH · Crystal structure of an intramolecular human telomeric DNA G-quadruplex bound by the… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 3UYH · PDBe 3UYH
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.