MolNFT v1 · #81611 · protein
Structure of an aminotransferase (degt-dnrj-ERYC1-strs family) from coxiella burnetii in complex with pmp
3UWC · Nucleotide-sugar aminotransferase: “Structure of an aminotransferase (degt-dnrj-ERYC1-strs family) from coxiella burnetii in complex with pmp”. X-ray diffraction, 2 ligands (PMP, NA), 1 pocket (best druggability 0.66). MolNFT v1…
- PDB
- 3UWC
- Type
- protein
- Length
- 371 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Nucleotide-sugar aminotransferase
- EC
- 2.6.1.-
- UniProt
- B5U8Q1
- Ligands
- PMP, NA
- Pockets
- 1 · best druggability 0.66
Structure
x-ray diffraction · 1 distinct chain · 42% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Nucleotide-sugar aminotransferase (EC 2.6.1.-) | protein | 371 | 42% helix, 18% strand | B5U8Q1 |
Ligands and binding sites
- PMP · 4'-deoxy-4'-aminopyridoxal-5'-phosphate · ligand · chains A
- NA · Sodium ion · metal · 3 copies · chains A
- DIO · 1,4-diethylene dioxide · additive · chains A
- EDO · 1,2-ethanediol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 220 | 0.66 | 0.84 | 44 | NA, EDO, PMP |
Modifications
Observed in the structure: 9 modified (engineered).
Compared structures
- 3UWC · Structure of an aminotransferase (DegT-DnrJ-EryC1-StrS family) from Coxiella burnetii in… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B5U8Q1
- Elsewhere: RCSB PDB 3UWC · PDBe 3UWC · UniProt B5U8Q1
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