MolNFT v1 · #81529 · protein

Structure of the pilotin of the type II secretion system

3UTK · Lipoprotein outs: “Structure of the pilotin of the type II secretion system”. X-ray diffraction, 2 pockets (best druggability 0.55). MolNFT v1 #81529 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3UTK
Type: protein
Length: 190 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Lipoprotein outs
UniProt: Q01567
Pockets: 2 · best druggability 0.55

Structure

x-ray diffraction · 1 distinct chain · 72% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Lipoprotein outs	protein	95	72% helix, 0% strand	Q01567

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	100	0.55	0.84	21	empty
2	55	0.37	0.80	13	empty

Interfaces

1 interface between chains.

A–B · 592 Å² buried · 12 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

3UTK · Structure of the pilotin of the type II secretion system · the same entry in another collection · chain A against A, TM-score 1.00
Q01567 · AlphaFold monomer V2.0 prediction for pilotin outs (Q01567) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q01567
Elsewhere: RCSB PDB 3UTK · PDBe 3UTK · UniProt Q01567

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