MolNFT v1 · #80956 · protein
Crystal structure of a peptidyl-prolyl cis-trans isomerase E (ppie) from homo sapiens at 2.50 a resolution
3UCH: “Crystal structure of a peptidyl-prolyl cis-trans isomerase E (ppie) from homo sapiens at 2.50 a resolution”. X-ray diffraction, 1 pocket (best druggability 0.30). MolNFT v1 #80956 on GenesisL1: 3D structure, binding sites and…
- PDB
- 3UCH
- Type
- protein
- Length
- 173 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Peptidyl-prolyl cis-trans isomerase E
- EC
- 5.2.1.8
- UniProt
- Q9UNP9
- Pockets
- 1 · best druggability 0.30
Structure
x-ray diffraction · 1 distinct chain · 13% helix, 31% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Peptidyl-prolyl cis-trans isomerase E (EC 5.2.1.8) | protein | 173 | 13% helix, 31% strand | Q9UNP9 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 63 | 0.30 | 0.75 | 23 | empty |
Modifications
Observed in the structure: 5 modified (engineered).
Compared structures
- 3UCH · Crystal structure of a peptidyl-prolyl cis-trans isomerase E (PPIE) from Homo sapiens at… · the same entry in another collection · chain A against A, TM-score 1.00
- Q9UNP9 · AlphaFold monomer V2.0 prediction for peptidyl-prolyl cis-trans isomerase E (Q9UNP9) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9UNP9
- Elsewhere: RCSB PDB 3UCH · PDBe 3UCH · UniProt Q9UNP9
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