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MolNFT v1 · #80769 · protein + DNA

Crystal structure of ALBA2-DNA complex

3U6Y · DNA/RNA-binding protein alba 2: “Crystal structure of ALBA2-DNA complex”. X-ray diffraction, 1 ligand (PO4). MolNFT v1 #80769 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
3U6Y
Type
protein + DNA
Length
208 residues
Chains
4
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
DNA/RNA-binding protein alba 2; DNA (5'-D(*CP*CP*GP*GP*C)-3'); DNA…
UniProt
Q9YAX2
Ligands
PO4

Structure

x-ray diffraction · 3 distinct chains · 27% helix, 35% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A, CDNA/RNA-binding protein alba 2protein9927% helix, 35% strandQ9YAX2
DDNA (5'-D(*CP*CP*GP*GP*C)-3')dna5——
EDNA (5'-D(*GP*GP*CP*CP*G)-3')dna5——

Ligands and binding sites

  • PO4 · Phosphate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

4 interfaces between chains.

  • A–C · 816 Ų buried · 13 hydrogen bonds · protein-protein
  • D–E · 224 Ų buried · 20 hydrogen bonds · nucleic-nucleic
  • C–D · 45 Ų buried · 0 hydrogen bonds · protein-nucleic
  • C–E · 25 Ų buried · 0 hydrogen bonds · protein-nucleic

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

  • 3U6Y · Crystal structure of ALBA2-DNA complex · the same entry in another collection · chain C against C, TM-score 1.00
  • Q9YAX2 · AlphaFold monomer V2.0 prediction for DNA/RNA-binding protein alba 2 (Q9YAX2) · a predicted model of the same protein · chain C against A, TM-score 0.98

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