MolNFT v1 · #8030 · protein

B-glucosidase from streptomyces sp

1GON · Beta-glucosidase: “B-glucosidase from streptomyces sp”. X-ray diffraction, 2 ligands (HG, SO4), 5 pockets (best druggability 0.72). MolNFT v1 #8030 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1GON
Type: protein
Length: 893 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Beta-glucosidase
UniProt: Q59976
Ligands: HG, SO4
Pockets: 5 · best druggability 0.72

Structure

x-ray diffraction · 2 distinct chains · 42% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Beta-glucosidase	protein	447	43% helix, 16% strand	Q59976
B	Beta-glucosidase	protein	446	41% helix, 15% strand	Q59976

Ligands and binding sites

HG · Mercury (II) ion · metal · 6 copies · chains A, B
SO4 · Sulfate ion · ion · 3 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	445	0.72	0.82	37	HG
2	419	0.69	0.81	38	HG
3	60	0.45	0.83	15	empty
4	51	0.41	0.82	14	empty
5	50	0.37	0.80	17	empty

Interfaces

1 interface between chains.

A–B · 1038 Å² buried · 5 hydrogen bonds · protein-protein

Compared structures

1GON · b-glucosidase from Streptomyces sp · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q59976
Elsewhere: RCSB PDB 1GON · PDBe 1GON · UniProt Q59976

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.