MolNFT v1 · #79466 · protein
Crystal structure of HIV epitope-scaffold 4E10_1XIZA_S0_006_C
3T43: “Crystal structure of HIV epitope-scaffold 4E10_1XIZA_S0_006_C”. X-ray diffraction, 1 pocket (best druggability 0.78). MolNFT v1 #79466 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3T43
- Type
- protein
- Length
- 309 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- HIV epitope-scaffold 4E10_1XIZA_S0_006_C
- Pockets
- 1 · best druggability 0.78
Structure
x-ray diffraction · 2 distinct chains · 44% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | HIV epitope-scaffold 4E10_1XIZA_S0_006_C | protein | 155 | 44% helix, 23% strand | — |
| B | HIV epitope-scaffold 4E10_1XIZA_S0_006_C | protein | 154 | 44% helix, 23% strand | — |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 124 | 0.78 | 0.97 | 35 | empty |
Interfaces
1 interface between chains.
- A–B · 1126 Ų buried · 14 hydrogen bonds · protein-protein
Compared structures
- 3T43 · Crystal Structure of HIV Epitope-Scaffold 4E10_1XIZA_S0_006_C · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 3T43 · PDBe 3T43
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