MolNFT v1 · #79410 · protein
Fructose-1,6-bisphosphate ALDOLASE/PHOSPHATASE from thermoproteus neutrophilus, Y229F variant with dhap
3T2G: “Fructose-1,6-bisphosphate ALDOLASE/PHOSPHATASE from thermoproteus neutrophilus, Y229F variant with dhap”. X-ray diffraction, 2 ligands (13P, MG), 2 pockets (best druggability 0.60). MolNFT v1 #79410 on GenesisL1: 3D structure…
- PDB
- 3T2G
- Type
- protein
- Length
- 383 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Fructose-1,6-bisphosphate ALDOLASE/PHOSPHATASE
- EC
- 4.1.2.13, 3.1.3.11
- UniProt
- B1YAL1
- Ligands
- 13P, MG
- Pockets
- 2 · best druggability 0.60
Structure
x-ray diffraction · 1 distinct chain · 27% helix, 29% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Fructose-1,6-bisphosphate ALDOLASE/PHOSPHATASE (EC 4.1.2.13, 3.1.3.11) | protein | 383 | 27% helix, 29% strand | B1YAL1 |
Ligands and binding sites
- 13P · 1,3-dihydroxyacetonephosphate · ligand · 2 copies · chains A
- MG · Magnesium ion · metal · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 361 | 0.60 | 0.77 | 41 | 13P |
| 2 | 57 | 0.42 | 0.83 | 14 | empty |
Compared structures
- 3T2G · Fructose-1,6-bisphosphate aldolase/phosphatase from Thermoproteus neutrophilus, Y229F… · the same entry in another collection · chain A against A, TM-score 1.00
- B1YAL1 · AlphaFold monomer V2.0 prediction for fructose-1,6-bisphosphate ALDOLASE/PHOSPHATASE… · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B1YAL1
- Elsewhere: RCSB PDB 3T2G · PDBe 3T2G · UniProt B1YAL1
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