MolNFT v1 · #79113 · protein

Hypothetical protein PA2703 pseudomonas aeruginosa PAO1

3STQ · Putative uncharacterized protein: “Hypothetical protein PA2703 pseudomonas aeruginosa PAO1”. X-ray diffraction, 9 pockets (best druggability 0.64). MolNFT v1 #79113 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3STQ
Type: protein
Length: 507 residues
Chains: 6
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Putative uncharacterized protein
UniProt: Q9I0D9
Pockets: 9 · best druggability 0.64

Structure

x-ray diffraction · 3 distinct chains · 69% helix, 5% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, D, E	Putative uncharacterized protein	protein	86	72% helix, 7% strand	Q9I0D9
C	Putative uncharacterized protein	protein	86	69% helix, 1% strand	Q9I0D9
F	Putative uncharacterized protein	protein	77	66% helix, 6% strand	Q9I0D9

Pockets

9 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	587	0.64	0.75	48	empty
2	330	0.54	0.74	40	empty
3	110	0.52	0.82	21	empty
4	128	0.51	0.80	21	empty
5	124	0.39	0.75	22	empty

Interfaces

9 interfaces between chains.

B–F · 1511 Å² buried · 29 hydrogen bonds · protein-protein
A–E · 1490 Å² buried · 27 hydrogen bonds · protein-protein
E–F · 772 Å² buried · 8 hydrogen bonds · protein-protein
C–E · 478 Å² buried · 2 hydrogen bonds · protein-protein
A–D · 466 Å² buried · 2 hydrogen bonds · protein-protein

Compared structures

3STQ · Hypothetical protein PA2703 Pseudomonas aeruginosa PAO1 · the same entry in another collection · chain F against F, TM-score 1.00
Q9I0D9 · AlphaFold monomer V2.0 prediction for immune protein TSI2 (Q9I0D9) · a predicted model of the same protein · chain F against A, TM-score 0.87

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9I0D9
Elsewhere: RCSB PDB 3STQ · PDBe 3STQ · UniProt Q9I0D9

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