MolNFT v1 · #79008 · protein

Putative mga family transcriptional regulator from enterococcus faecalis

3SQN · Conserved domain protein: “Putative mga family transcriptional regulator from enterococcus faecalis”. X-ray diffraction, 9 pockets (best druggability 0.73). MolNFT v1 #79008 on GenesisL1: 3D structure, binding sites and pockets in…

PDB: 3SQN
Type: protein
Length: 849 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Conserved domain protein
UniProt: Q82ZN7
Pockets: 9 · best druggability 0.73

Structure

x-ray diffraction · 2 distinct chains · 59% helix, 9% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Conserved domain protein	protein	468	58% helix, 10% strand	Q82ZN7
B	Conserved domain protein	protein	381	60% helix, 8% strand	Q82ZN7

Pockets

9 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	545	0.73	0.81	61	empty
2	84	0.57	0.86	22	empty
3	67	0.55	0.87	17	empty
4	130	0.46	0.77	19	empty
5	137	0.39	0.74	26	empty

Interfaces

1 interface between chains.

A–B · 3312 Å² buried · 24 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 9 modified (engineered).

Compared structures

3SQN · Putative Mga family transcriptional regulator from Enterococcus faecalis · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q82ZN7
Elsewhere: RCSB PDB 3SQN · PDBe 3SQN · UniProt Q82ZN7

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