MolNFT v1 · #79001 · protein
Crystal structure of monomeric M-pmv retroviral protease
3SQF: “Crystal structure of monomeric M-pmv retroviral protease”. X-ray diffraction, 2 pockets (best druggability 0.39). MolNFT v1 #79001 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 3SQF
- Type
- protein
- Length
- 189 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protease
- EC
- 3.4.23.-
- UniProt
- P07570
- Pockets
- 2 · best druggability 0.39
Structure
x-ray diffraction · 2 distinct chains · 11% helix, 38% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protease (EC 3.4.23.-) | protein | 95 | 11% helix, 37% strand | P07570 |
| B | Protease (EC 3.4.23.-) | protein | 94 | 11% helix, 38% strand | P07570 |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 79 | 0.39 | 0.78 | 24 | empty |
| 2 | 82 | 0.35 | 0.75 | 22 | empty |
Interfaces
1 interface between chains.
- A–B · 842 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
- 3SQF · Crystal structure of monomeric M-PMV retroviral protease · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P07570
- Elsewhere: RCSB PDB 3SQF · PDBe 3SQF · UniProt P07570
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