MolNFT v1 · #78626 · protein

SEM5 SH3 domain complexed with peptoid inhibitor

3SEM · Sex muscle abnormal protein 5: “SEM5 SH3 domain complexed with peptoid inhibitor”. X-ray diffraction. MolNFT v1 #78626 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 3SEM
Type: protein
Length: 129 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Sex muscle abnormal protein 5; SH3 peptoid inhibitor
UniProt: P29355

Structure

x-ray diffraction · 3 distinct chains · 4% helix, 39% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Sex muscle abnormal protein 5	protein	58	5% helix, 48% strand	P29355
C	SH3 peptoid inhibitor	protein	7	0% helix, 0% strand	—
D	SH3 peptoid inhibitor	protein	6	0% helix, 0% strand	—

Interfaces

3 interfaces between chains.

A–C · 397 Å² buried · 4 hydrogen bonds · protein-protein
B–D · 322 Å² buried · 3 hydrogen bonds · protein-protein
A–B · 241 Å² buried · 3 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 modified, 1 disulfide (nonstandard, disulfide).

Compared structures

3SEM · SEM5 SH3 domain complexed with peptoid inhibitor · the same entry in another collection · chain A against A, TM-score 1.00
P29355 · AlphaFold monomer V2.0 prediction for sex muscle abnormal protein 5 (P29355) · a predicted model of the same protein · chain A against A, TM-score 0.94

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P29355
Elsewhere: RCSB PDB 3SEM · PDBe 3SEM · UniProt P29355

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.