MolNFT v1 · #78581 · protein
Crystal structure of C176A mutant of glutamine-dependent NAD+ synthetase from M. tuberculosis in apo form
3SDB · Glutamine-dependent NAD(+) synthetase: “Crystal structure of C176A mutant of glutamine-dependent NAD+ synthetase from M. tuberculosis in apo form”. X-ray diffraction, 7 pockets (best druggability 0.69). MolNFT v1 #78581 on…
- PDB
- 3SDB
- Type
- protein
- Length
- 647 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Glutamine-dependent NAD(+) synthetase
- EC
- 6.3.5.1
- UniProt
- P0A5L6
- Pockets
- 7 · best druggability 0.69
Structure
x-ray diffraction · 1 distinct chain · 44% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Glutamine-dependent NAD(+) synthetase (EC 6.3.5.1) | protein | 647 | 44% helix, 18% strand | P0A5L6 |
Pockets
7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 369 | 0.69 | 0.82 | 31 | empty |
| 2 | 588 | 0.69 | 0.78 | 61 | empty |
| 3 | 79 | 0.54 | 0.85 | 19 | empty |
| 4 | 67 | 0.50 | 0.85 | 20 | empty |
| 5 | 67 | 0.34 | 0.76 | 16 | empty |
Compared structures
- 3SDB · Crystal structure of C176A mutant of glutamine-dependent NAD+ synthetase from M.… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0A5L6
- Elsewhere: RCSB PDB 3SDB · PDBe 3SDB · UniProt P0A5L6
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